Human plasma extrinsic pathway inhibitor activity: I. Standardization of assay and evaluation of physiologic variables
نویسندگان
چکیده
منابع مشابه
Human plasma extrinsic pathway inhibitor activity: I. Standardization of assay and evaluation of physiologic variables.
An assay was standardized to measure extrinsic pathway inhibitor (EPI) activity in human plasma. Variables that could potentially influence its measurement were systematically examined. The coefficient of variation of the assay was 6.3% for the same sample assayed on different days. The linear regression line for a plot of observed v expected values of mixtures of plasmas with different EPI lev...
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Plasma or serum extrinsic pathway inhibitor (EPI) activity was measured in 24 patients with disseminated intravascular coagulation (DIC) and in 23 patients with severe hepatocellular disease. EPI was measured as activity in a test sample that inhibitied factor VIla/tissue factor (TF)catalyzed activation of 3H-factor IX (activation peptide release) in the presence of factor X. Of the 24 patients...
متن کاملHuman plasma extrinsic pathway inhibitor activity: II. Plasma levels in disseminated intravascular coagulation and hepatocellular disease.
Plasma or serum extrinsic pathway inhibitor (EPI) activity was measured in 24 patients with disseminated intravascular coagulation (DIC) and in 23 patients with severe hepatocellular disease. EPI was measured as activity in a test sample that inhibited factor VIIa/tissue factor (TF)-catalyzed activation of 3H-factor IX (activation peptide release) in the presence of factor X. Of the 24 patients...
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ژورنال
عنوان ژورنال: Blood
سال: 1989
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v74.1.201.201